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In transcription antitermination by Qλ, NusA induces refolding of Qλ to form a nozzle that extends the RNA polymerase RNA-exit channel

Lambdoid bacteriophage Q proteins are transcription antipausing and antitermination factors that enable RNA polymerase (RNAP) to read through pause and termination sites. Q proteins load onto RNAP engaged in promoter-proximal pausing at a Q binding element (QBE) and adjacent sigma-dependent pause el...

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Detalles Bibliográficos
Autores principales: Yin, Zhou, Bird, Jeremy G., Kaelber, Jason T., Nickels, Bryce E., Ebright, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388147/
https://www.ncbi.nlm.nih.gov/pubmed/35951650
http://dx.doi.org/10.1073/pnas.2205278119