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A highly efficacious live attenuated mumps virus–based SARS-CoV-2 vaccine candidate expressing a six-proline stabilized prefusion spike

With the rapid increase in SARS-CoV-2 cases in children, a safe and effective vaccine for this population is urgently needed. The MMR (measles/mumps/rubella) vaccine has been one of the safest and most effective human vaccines used in infants and children since the 1960s. Here, we developed live att...

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Detalles Bibliográficos
Autores principales: Zhang, Yuexiu, Lu, Mijia, Mahesh, K C, Kim, Eunsoo, Shamseldin, Mohamed M., Ye, Chengjin, Dravid, Piyush, Chamblee, Michelle, Park, Jun-Gyu, Hall, Jesse M., Trivedi, Sheetal, Chaiwatpongsakorn, Supranee, Kenny, Adam D., Murthy, Satyapramod Srinivasa, Sharma, Himanshu, Liang, Xueya, Yount, Jacob S., Kapoor, Amit, Martinez-Sobrido, Luis, Dubey, Purnima, Boyaka, Prosper N., Peeples, Mark E., Li, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388148/
https://www.ncbi.nlm.nih.gov/pubmed/35895717
http://dx.doi.org/10.1073/pnas.2201616119