PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques

Programmed death-1 (PD-1) blockade during chronic Simian immunodeficiency virus (SIV) infection results in restoration of CD8 T-cell function and enhances viral control. Here, we tested the therapeutic benefits of PD-1 blockade administered soon after anti-retrovial therapy (ART) interruption (ATI)...

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Detalles Bibliográficos
Autores principales: Velu, Vijayakumar, Titanji, Kehmia, Ahmed, Hasan, Shetty, Ravi Dyavar, Chennareddi, Lakshmi S., Freeman, Gordon J., Ahmed, Rafi, Amara, Rama Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388156/
https://www.ncbi.nlm.nih.gov/pubmed/35939675
http://dx.doi.org/10.1073/pnas.2202148119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388156/
https://www.ncbi.nlm.nih.gov/pubmed/35939675
http://dx.doi.org/10.1073/pnas.2202148119

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