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The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery

Although patients generally prefer oral drug delivery to injections, low permeability of the gastrointestinal tract makes this method impossible for most biomacromolecules. One potential solution is codelivery of macromolecules, including therapeutic proteins or nucleic acids, with intestinal permea...

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Detalles Bibliográficos
Autores principales: Lamson, Nicholas G., Fein, Katherine C., Gleeson, John P., Newby, Alexandra N., Xian, Sijie, Cochran, Kyle, Chaudhary, Namit, Melamed, Jilian R., Ball, Rebecca L., Suri, Kanika, Ahuja, Vishal, Zhang, Anna, Berger, Adrian, Kolodieznyi, Dmytro, Schmidt, Brigitte F., Silva, Gloria L., Whitehead, Kathryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388159/
https://www.ncbi.nlm.nih.gov/pubmed/35943988
http://dx.doi.org/10.1073/pnas.2207829119