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A 3-Mbp fragment on rat chromosome 1 affects susceptibility both to stroke and kidney injury under salt loading in the stroke-prone spontaneously hypertensive rat: a genetic approach using multiple congenic strains

We have previously reported that a major quantitative trait locus (QTL) responsible for susceptibility to salt-induced stroke in the stroke-prone spontaneously hypertensive rat (SHRSP) is located in a 3-Mbp region on chromosome 1 covered by SHRSP.SHR-(D1Rat23-D1Rat213)/Izm (termed Pr1.31), a congeni...

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Detalles Bibliográficos
Autores principales: Wang, Mei, Ohara, Hiroki, Egawa, Masahiro, Fukunaga, Shohei, Matsuo, Hiroyuki, Ge, Zhi-Ru, Nabika, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388333/
https://www.ncbi.nlm.nih.gov/pubmed/35354714
http://dx.doi.org/10.1538/expanim.21-0189