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The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-17
Clec1A, a member of C-type lectin receptor family, has a carbohydrate recognition domain in its extracellular region, but no known signaling motif in the cytoplasmic domain. Clec1a is highly expressed in endothelial cells and weakly in dendritic cells. Although this molecule was reported to play an...
Autores principales: | Makusheva, Yulia, Chung, Soo-Hyun, Akitsu, Aoi, Maeda, Natsumi, Maruhashi, Takumi, Ye, Xiao-Qi, Kaifu, Tomonori, Saijo, Shinobu, Sun, Haiyang, Han, Wei, Tang, Ce, Iwakura, Yoichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Association for Laboratory Animal Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388343/ https://www.ncbi.nlm.nih.gov/pubmed/35135958 http://dx.doi.org/10.1538/expanim.21-0191 |
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