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Organoid technology and lung injury mouse models evaluating effects of hydroxychloroquine on lung epithelial regeneration

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) damages lung epithelial stem/progenitor cells. Ideal anti-SARS-CoV-2 drug candidates should be screened to prevent secondary injury to the lungs. Here, we propose that in vitro three-dimensional organoid and lung injury repair mouse models...

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Detalles Bibliográficos
Autores principales: Zhao, Fuxiaonan, Wang, Jianhai, Wang, Qi, Hou, Zhili, Zhang, Yingchao, Li, Xue, Wu, Qi, Chen, Huaiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388344/
https://www.ncbi.nlm.nih.gov/pubmed/35197405
http://dx.doi.org/10.1538/expanim.21-0168