Role of H4K16 acetylation in 53BP1 recruitment to double-strand break sites in in vitro aged cells

Increased frequency of DNA double strand breaks (DSBs) with aging suggests an age-associated decline in DSB repair efficiency, which is also influenced by the epigenetic landscape. H4 acetylation at lysine 16 (H4K16Ac) has been related to DSB repair since deacetylation of this mark is required for e...

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Detalles Bibliográficos
Autores principales: González-Bermúdez, Lourdes, Genescà, Anna, Terradas, Mariona, Martín, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388460/
https://www.ncbi.nlm.nih.gov/pubmed/35851632
http://dx.doi.org/10.1007/s10522-022-09979-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388460/
https://www.ncbi.nlm.nih.gov/pubmed/35851632
http://dx.doi.org/10.1007/s10522-022-09979-6

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