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Role of H4K16 acetylation in 53BP1 recruitment to double-strand break sites in in vitro aged cells
Increased frequency of DNA double strand breaks (DSBs) with aging suggests an age-associated decline in DSB repair efficiency, which is also influenced by the epigenetic landscape. H4 acetylation at lysine 16 (H4K16Ac) has been related to DSB repair since deacetylation of this mark is required for e...
Autores principales: | González-Bermúdez, Lourdes, Genescà, Anna, Terradas, Mariona, Martín, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388460/ https://www.ncbi.nlm.nih.gov/pubmed/35851632 http://dx.doi.org/10.1007/s10522-022-09979-6 |
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