Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer’s disease

To better understand DNA methylation in Alzheimer’s disease (AD) from both mechanistic and biomarker perspectives, we performed an epigenome-wide meta-analysis of blood DNA methylation in two large independent blood-based studies in AD, the ADNI and AIBL studies, and identified 5 CpGs, mapped to the...

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Detalles Bibliográficos
Autores principales: C. Silva, Tiago, Young, Juan I., Zhang, Lanyu, Gomez, Lissette, Schmidt, Michael A., Varma, Achintya, Chen, X. Steven, Martin, Eden R., Wang, Lily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388493/
https://www.ncbi.nlm.nih.gov/pubmed/35982059
http://dx.doi.org/10.1038/s41467-022-32475-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388493/
https://www.ncbi.nlm.nih.gov/pubmed/35982059
http://dx.doi.org/10.1038/s41467-022-32475-x

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