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Rapid-SL identifies synthetic lethal sets with an arbitrary cardinality

The multidrug resistance of numerous pathogenic microorganisms is a serious challenge that raises global healthcare concerns. Multi-target medications and combinatorial therapeutics are much more effective than single-target drugs due to their synergistic impact on the systematic activities of micro...

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Detalles Bibliográficos
Autores principales: Dehghan Manshadi, Mehdi, Setoodeh, Payam, Zare, Habil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388495/
https://www.ncbi.nlm.nih.gov/pubmed/35982201
http://dx.doi.org/10.1038/s41598-022-18177-w