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Novel mechanisms underlying inhibition of inflammation-induced angiogenesis by dexamethasone and gentamicin via PI3K/AKT/NF-κB/VEGF pathways in acute radiation proctitis

Acute radiation proctitis (ARP) is one of the most common complications of pelvic radiotherapy attributed to radiation exposure. The mechanisms of ARP are related to inflammation, angiogenesis, and so on. In this study we evaluated the effect of dexamethasone (DXM) combined with gentamicin (GM) enem...

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Detalles Bibliográficos
Autores principales: Li, Yousong, Ding, Qin, Gao, Jinsheng, Li, Chunxia, Hou, Pengxiao, Xu, Jie, Cao, Kaiqi, Hu, Min, Cheng, Lin, Wang, Xixing, Yang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388498/
https://www.ncbi.nlm.nih.gov/pubmed/35982137
http://dx.doi.org/10.1038/s41598-022-17981-8