Chemical zymogens for the protein cysteinome

We present three classes of chemical zymogens established around the protein cysteinome. In each case, the cysteine thiol group was converted into a mixed disulfide: with a small molecule, a non-degradable polymer, or with a fast-depolymerizing fuse polymer (Z(LA)). The latter was a polydisulfide ba...

Descripción completa

Detalles Bibliográficos
Autores principales: Montasell, Mireia Casanovas, Monge, Pere, Carmali, Sheiliza, Dias Loiola, Livia Mesquita, Andersen, Dante Guldbrandsen, Løvschall, Kaja Borup, Søgaard, Ane Bretschneider, Kristensen, Maria Merrild, Pütz, Jean Maurice, Zelikin, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388531/
https://www.ncbi.nlm.nih.gov/pubmed/35982075
http://dx.doi.org/10.1038/s41467-022-32609-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388531/
https://www.ncbi.nlm.nih.gov/pubmed/35982075
http://dx.doi.org/10.1038/s41467-022-32609-1

Ejemplares similares