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Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota

The gut microbiome is an important determinant in various diseases. Here we perform a cross-sectional study of Japanese adults and identify the Blautia genus, especially B. wexlerae, as a commensal bacterium that is inversely correlated with obesity and type 2 diabetes mellitus. Oral administration...

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Detalles Bibliográficos
Autores principales: Hosomi, Koji, Saito, Mayu, Park, Jonguk, Murakami, Haruka, Shibata, Naoko, Ando, Masahiro, Nagatake, Takahiro, Konishi, Kana, Ohno, Harumi, Tanisawa, Kumpei, Mohsen, Attayeb, Chen, Yi-An, Kawashima, Hitoshi, Natsume-Kitatani, Yayoi, Oka, Yoshimasa, Shimizu, Hidenori, Furuta, Mari, Tojima, Yoko, Sawane, Kento, Saika, Azusa, Kondo, Saki, Yonejima, Yasunori, Takeyama, Haruko, Matsutani, Akira, Mizuguchi, Kenji, Miyachi, Motohiko, Kunisawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388534/
https://www.ncbi.nlm.nih.gov/pubmed/35982037
http://dx.doi.org/10.1038/s41467-022-32015-7