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Differential ion mobility mass spectrometry in immunopeptidomics identifies neoantigens carrying colorectal cancer driver mutations

Understanding the properties of human leukocyte antigen (HLA) peptides (immunopeptides) is essential for precision cancer medicine, while the direct identification of immunopeptides from small biopsies of clinical tissues by mass spectrometry (MS) is still confronted with technical challenges. Here,...

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Detalles Bibliográficos
Autores principales: Minegishi, Yuriko, Kiyotani, Kazuma, Nemoto, Kensaku, Inoue, Yoshikage, Haga, Yoshimi, Fujii, Risa, Saichi, Naomi, Nagayama, Satoshi, Ueda, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388627/
https://www.ncbi.nlm.nih.gov/pubmed/35982173
http://dx.doi.org/10.1038/s42003-022-03807-w