Evidence of a genetically driven metabolomic signature in actively inflamed Crohn’s disease

Crohn’s disease (CD) is characterised by chronic inflammation. We aimed to identify a relationship between plasma inflammatory metabolomic signature and genomic data in CD using blood plasma metabolic profiles. Proton NMR spectroscopy were achieved for 228 paediatric CD patients. Regression (OPLS) m...

Descripción completa

Detalles Bibliográficos
Autores principales: Mossotto, Enrico, Boberska, Joanna, Ashton, James J., Stafford, Imogen S., Cheng, Guo, Baker, Jonathan, Borca, Florina, Phan, Hang T. T., Coelho, Tracy F., Beattie, R. Mark, Claus, Sandrine P., Ennis, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388636/
https://www.ncbi.nlm.nih.gov/pubmed/35982195
http://dx.doi.org/10.1038/s41598-022-18178-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388636/
https://www.ncbi.nlm.nih.gov/pubmed/35982195
http://dx.doi.org/10.1038/s41598-022-18178-9

Ejemplares similares