Evidence of a genetically driven metabolomic signature in actively inflamed Crohn’s disease

Crohn’s disease (CD) is characterised by chronic inflammation. We aimed to identify a relationship between plasma inflammatory metabolomic signature and genomic data in CD using blood plasma metabolic profiles. Proton NMR spectroscopy were achieved for 228 paediatric CD patients. Regression (OPLS) m...

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Detalles Bibliográficos
Autores principales: Mossotto, Enrico, Boberska, Joanna, Ashton, James J., Stafford, Imogen S., Cheng, Guo, Baker, Jonathan, Borca, Florina, Phan, Hang T. T., Coelho, Tracy F., Beattie, R. Mark, Claus, Sandrine P., Ennis, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388636/
https://www.ncbi.nlm.nih.gov/pubmed/35982195
http://dx.doi.org/10.1038/s41598-022-18178-9

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