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Heterogeneity of circulating CD4(+)CD8(+) double-positive T cells characterized by scRNA-seq analysis and trajectory inference
The frequency of CD4(+)CD8(+) double-positive (DP) T cells is highly associated with a variety of diseases. Recently, we used high-throughput single-cell RNA sequencing to show that circulating DP T cells in cynomolgus monkeys comprise nine heterogeneous populations. To better understand the charact...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388645/ https://www.ncbi.nlm.nih.gov/pubmed/35982155 http://dx.doi.org/10.1038/s41598-022-18340-3 |