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Heterogeneity of circulating CD4(+)CD8(+) double-positive T cells characterized by scRNA-seq analysis and trajectory inference

The frequency of CD4(+)CD8(+) double-positive (DP) T cells is highly associated with a variety of diseases. Recently, we used high-throughput single-cell RNA sequencing to show that circulating DP T cells in cynomolgus monkeys comprise nine heterogeneous populations. To better understand the charact...

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Detalles Bibliográficos
Autores principales: Choi, Sung Min, Park, Hi Jung, Choi, Eun A, Jung, Kyeong Cheon, Lee, Jae Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388645/
https://www.ncbi.nlm.nih.gov/pubmed/35982155
http://dx.doi.org/10.1038/s41598-022-18340-3