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Cytidine deaminase activity increases in the blood of breast cancer patients

Cytidine deaminase (CDA), an enzyme of the pyrimidine salvage pathway, deaminates cytidine, deoxycytidine and analogs, such as gemcitabine. Constitutive low levels of CDA activity have been reported in the blood of patients with hematological malignancies or suffering from gemcitabine toxicity. We p...

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Detalles Bibliográficos
Autores principales: Buhagiar-Labarchède, Géraldine, Onclercq-Delic, Rosine, Vacher, Sophie, Berger, Frédérique, Bièche, Ivan, Stoppa-Lyonnet, Dominique, Amor-Guéret, Mounira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388666/
https://www.ncbi.nlm.nih.gov/pubmed/35982128
http://dx.doi.org/10.1038/s41598-022-18462-8