Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs

Nociception and motor coordination are critically governed by glycine receptor (GlyR) function at inhibitory synapses. Consequentially, GlyRs are attractive targets in the management of chronic pain and in the treatment of several neurological disorders. High-resolution mechanistic details of GlyR f...

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Detalles Bibliográficos
Autores principales: Kumar, Arvind, Kindig, Kayla, Rao, Shanlin, Zaki, Afroditi-Maria, Basak, Sandip, Sansom, Mark S. P., Biggin, Philip C., Chakrapani, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388682/
https://www.ncbi.nlm.nih.gov/pubmed/35982060
http://dx.doi.org/10.1038/s41467-022-32594-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388682/
https://www.ncbi.nlm.nih.gov/pubmed/35982060
http://dx.doi.org/10.1038/s41467-022-32594-5

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