Radiosynthesis and First Preclinical Evaluation of the Novel (11)C-Labeled FAP Inhibitor (11)C-FAPI: A Comparative Study of (11)C-FAPIs and ((68)Ga) Ga-DOTA-FAPI-04 in a High–FAP-Expression Mouse Model

Purpose: (68)Ga-labeled fibroblast activation protein inhibitors, such as [(68)Ga]Ga-DOTA-FAPI-04 and [(68)Ga]Ga-DOTA-FAPI-46, have been successfully applied in positron emission tomography imaging of various tumor types. To broaden the PET tracers of different positron nuclides for imaging studies...

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Detalles Bibliográficos
Autores principales: Wang, Cheng, Hu, Zhoumi, Ding, Fan, Zhao, Haitao, Du, Fuqiang, Lv, Chun, Li, Lianghua, Huang, Gang, Liu, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388731/
https://www.ncbi.nlm.nih.gov/pubmed/35991604
http://dx.doi.org/10.3389/fchem.2022.939160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388731/
https://www.ncbi.nlm.nih.gov/pubmed/35991604
http://dx.doi.org/10.3389/fchem.2022.939160

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