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Regulation of cocaine seeking behavior by locus coeruleus noradrenergic activity in the ventral tegmental area is time- and contingency-dependent

Substance use disorder is linked to impairments in the ventral tegmental area (VTA) dopamine (DA) reward system. Noradrenergic (NA) inputs from locus coeruleus (LC) into VTA have been shown to modulate VTA neuronal activity, and are implicated in psychostimulant effects. Phasic LC activity controls...

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Detalles Bibliográficos
Autores principales: Solecki, Wojciech B., Kielbinski, Michał, Wilczkowski, Michał, Zajda, Katarzyna, Karwowska, Karolina, Joanna, Bernacka, Rajfur, Zenon, Przewłocki, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388848/
https://www.ncbi.nlm.nih.gov/pubmed/35992934
http://dx.doi.org/10.3389/fnins.2022.967969