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A survey of genome-wide association studies, polygenic scores and UK Biobank highlights resources for autoimmune disease genetics

Autoimmune diseases share a general mechanism of auto-antigens harming tissues. Still. they are phenotypically diverse, with genetic as well as environmental factors contributing to their etiology at varying degrees. Associated genomic loci and variants have been identified in numerous genome-wide a...

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Detalles Bibliográficos
Autores principales: Saurabh, Rochi, Fouodo, Césaire J. K., König, Inke R., Busch, Hauke, Wohlers, Inken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388859/
https://www.ncbi.nlm.nih.gov/pubmed/35990650
http://dx.doi.org/10.3389/fimmu.2022.972107