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Prenatal androgen treatment impairs the suprachiasmatic nucleus arginine-vasopressin to kisspeptin neuron circuit in female mice

Polycystic ovary syndrome (PCOS) is associated with elevated androgen and luteinizing hormone (LH) secretion and with oligo/anovulation. Evidence indicates that elevated androgens impair sex steroid hormone feedback regulation of pulsatile LH secretion. Hyperandrogenemia in PCOS may also disrupt the...

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Detalles Bibliográficos
Autores principales: Jamieson, Bradley B., Moore, Aleisha M., Lohr, Dayanara B., Thomas, Simone X., Coolen, Lique M., Lehman, Michael N., Campbell, Rebecca E., Piet, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388912/
https://www.ncbi.nlm.nih.gov/pubmed/35992143
http://dx.doi.org/10.3389/fendo.2022.951344