Hyperglycemia aggravates ischemic brain damage via ERK1/2 activated cell autophagy and mitochondrial fission

BACKGROUND: Hyperglycemia is one of the major risk factors for stroke and stroke recurrence, leading to aggravated neuronal damage after cerebral ischemia/reperfusion (I/R). ERK1/2 signaling pathway plays a vital role in cerebral ischemic injury. However, the role of the ERK1/2 pathway in hyperglyce...

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Detalles Bibliográficos
Autores principales: Liu, Ping, Yang, Xiao, Niu, Jianguo, Hei, Changchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388937/
https://www.ncbi.nlm.nih.gov/pubmed/35992111
http://dx.doi.org/10.3389/fendo.2022.928591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388937/
https://www.ncbi.nlm.nih.gov/pubmed/35992111
http://dx.doi.org/10.3389/fendo.2022.928591

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