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Hyperglycemia aggravates ischemic brain damage via ERK1/2 activated cell autophagy and mitochondrial fission
BACKGROUND: Hyperglycemia is one of the major risk factors for stroke and stroke recurrence, leading to aggravated neuronal damage after cerebral ischemia/reperfusion (I/R). ERK1/2 signaling pathway plays a vital role in cerebral ischemic injury. However, the role of the ERK1/2 pathway in hyperglyce...
Autores principales: | Liu, Ping, Yang, Xiao, Niu, Jianguo, Hei, Changchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388937/ https://www.ncbi.nlm.nih.gov/pubmed/35992111 http://dx.doi.org/10.3389/fendo.2022.928591 |
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