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Inhibition of IL1R1 or CASP4 attenuates spinal cord injury through ameliorating NLRP3 inflammasome-induced pyroptosis

Spinal cord injury (SCI) is a devastating trauma characterized by serious neuroinflammation and permanent neurological dysfunction. However, the molecular mechanism of SCI remains unclear, and few effective medical therapies are available at present. In this study, multiple bioinformatics methods we...

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Detalles Bibliográficos
Autores principales: Wang, Chenfeng, Ma, Hongdao, Zhang, Bangke, Hua, Tong, Wang, Haibin, Wang, Liang, Han, Lin, Li, Qisheng, Wu, Weiqing, Sun, Yulin, Yang, Haisong, Lu, Xuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389052/
https://www.ncbi.nlm.nih.gov/pubmed/35990672
http://dx.doi.org/10.3389/fimmu.2022.963582