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LNA-anti-miR-150 alleviates renal interstitial fibrosis by reducing pro-inflammatory M1/M2 macrophage polarization

Renal interstitial fibrosis (RIF) is a common pathological feature contributing to chronic injury and maladaptive repair following acute kidney injury. Currently, there is no effective therapy for RIF. We have reported that locked nuclear acid (LNA)-anti-miR-150 antagonizes pro-fibrotic pathways in...

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Detalles Bibliográficos
Autores principales: Hao, Xiangnan, Luan, Junjun, Jiao, Congcong, Ma, Cong, Feng, Zixuan, Zhu, Lingzi, Zhang, Yixiao, Fu, Jingqi, Lai, Enyin, Zhang, Beiru, Wang, Yanqiu, Kopp, Jeffrey B., Pi, Jingbo, Zhou, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389080/
https://www.ncbi.nlm.nih.gov/pubmed/35990680
http://dx.doi.org/10.3389/fimmu.2022.913007