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Metabolic heterogeneity caused by HLA-DRB1*04:05 and protective effect of inosine on autoimmune hepatitis

Autoimmune hepatitis (AIH) is an autoimmune disease caused by disruption of liver immune homeostasis. Genetic studies have revealed the predisposition of AIH with the human leukocyte antigen (HLA) region. Recently, metabolomics integrated with genomics has identified many genetic loci of biomedical...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Zhou, Leyu, Shen, Yi, Zhao, Shenglan, Zheng, Yanyi, Men, Ruoting, Fan, Xiaoli, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389112/
https://www.ncbi.nlm.nih.gov/pubmed/35990653
http://dx.doi.org/10.3389/fimmu.2022.982186