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Amyloid pathology induces dysfunction of systemic neurotransmission in aged APPswe/PS2 mice

This study aimed to investigate how amyloid pathology affects the functional aspects of neurotransmitter systems in Alzheimer’s disease. APPswe/PS2 mice (21 months of age) and wild-type (WT) mice underwent positron emission tomography (PET) and magnetic resonance spectroscopy (MRS). First, we obtain...

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Detalles Bibliográficos
Autores principales: Oh, Se Jong, Lee, Namhun, Nam, Kyung Rok, Kang, Kyung Jun, Han, Sang Jin, Lee, Kyo Chul, Lee, Yong Jin, Choi, Jae Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389227/
https://www.ncbi.nlm.nih.gov/pubmed/35992913
http://dx.doi.org/10.3389/fnins.2022.930613