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Connective tissue growth factor-targeting DNA aptamer suppresses pannus formation as diagnostics and therapeutics for rheumatoid arthritis

Connective tissue growth factor (CTGF) has been recently acknowledged as an ideal biomarker in the early disease course, participating in the pathogenesis of pannus formation in rheumatoid arthritis (RA). However, existing approaches for the detection of or antagonist targeting CTGF are either lacki...

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Detalles Bibliográficos
Autores principales: Wu, Gan, Liu, Can, Cao, Ben, Cao, Zelin, Zhai, Haige, Liu, Bin, Jin, Shengwei, Yang, Xinyu, Lv, Chen, Wang, Jianguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389230/
https://www.ncbi.nlm.nih.gov/pubmed/35990694
http://dx.doi.org/10.3389/fimmu.2022.934061