Jagged-1 is induced by mTOR inhibitors in renal cancer cells through an Akt/ALK5/Smad4-dependent mechanism

The mammalian target of rapamycin (mTOR) plays an important role in the aggressiveness and therapeutic resistance of many cancers. Targeting mTOR continues to be under clinical investigation for cancer therapy. Despite the notable clinical success of mTOR inhibitors in extending the overall survival...

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Detalles Bibliográficos
Autores principales: Danielpour, David, Corum, Sarah, Leahy, Patrick, Bangalore, Anusha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389240/
https://www.ncbi.nlm.nih.gov/pubmed/35992379
http://dx.doi.org/10.1016/j.crphar.2022.100117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389240/
https://www.ncbi.nlm.nih.gov/pubmed/35992379
http://dx.doi.org/10.1016/j.crphar.2022.100117

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