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A stress-blinded Atf1 can fully assemble heterochromatin in a RNAi-independent minimal mat locus but impairs directionality of mat2/3 switching

The MAP kinase Sty1 phosphorylates and activates the transcription factor Atf1 in response to several stress conditions, which then shifts from a transcriptional repressor to an activator. Atf1 also participates in heterochromatin assembly at the mat locus, in combination with the RNA interference (...

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Detalles Bibliográficos
Autores principales: Fraile, Rodrigo, Sánchez-Mir, Laura, Murciano-Julià, Guillem, Ayté, José, Hidalgo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389250/
https://www.ncbi.nlm.nih.gov/pubmed/35992058
http://dx.doi.org/10.1016/j.isci.2022.104820