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A stress-blinded Atf1 can fully assemble heterochromatin in a RNAi-independent minimal mat locus but impairs directionality of mat2/3 switching
The MAP kinase Sty1 phosphorylates and activates the transcription factor Atf1 in response to several stress conditions, which then shifts from a transcriptional repressor to an activator. Atf1 also participates in heterochromatin assembly at the mat locus, in combination with the RNA interference (...
Autores principales: | Fraile, Rodrigo, Sánchez-Mir, Laura, Murciano-Julià, Guillem, Ayté, José, Hidalgo, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389250/ https://www.ncbi.nlm.nih.gov/pubmed/35992058 http://dx.doi.org/10.1016/j.isci.2022.104820 |
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