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Plasma cells arise from differentiation of clonal lymphocytes and secrete IgM in Waldenström macroglobulinemia
Waldenström macroglobulinemia (WM) is characterized by bone marrow infiltration with malignant lymphoplasmacytic cells (LPCs), a smaller population of plasma cells (PCs), and hypersecretion of IgM monoclonal protein. Here, we show that CD45(low), CD38(+), and CD138(+) PCs and CD45(high), CD38(−), CD...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389254/ https://www.ncbi.nlm.nih.gov/pubmed/35992066 http://dx.doi.org/10.1016/j.isci.2022.104856 |