Plasma cells arise from differentiation of clonal lymphocytes and secrete IgM in Waldenström macroglobulinemia

Waldenström macroglobulinemia (WM) is characterized by bone marrow infiltration with malignant lymphoplasmacytic cells (LPCs), a smaller population of plasma cells (PCs), and hypersecretion of IgM monoclonal protein. Here, we show that CD45(low), CD38(+), and CD138(+) PCs and CD45(high), CD38(−), CD...

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Detalles Bibliográficos
Autores principales: Lim, Jun Hee, Wang, James Q., Webb, Fiona, Saxena, Kartik, Enosi Tuipulotu, Daniel, Pandey, Abhimanu, Man, Si Ming, Talaulikar, Dipti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389254/
https://www.ncbi.nlm.nih.gov/pubmed/35992066
http://dx.doi.org/10.1016/j.isci.2022.104856

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