Increased NOS coupling by the metabolite tetrahydrobiopterin (BH4) reduces preeclampsia/IUGR consequences

Preeclampsia (PE) is a high-prevalence pregnancy disease characterized by placental insufficiency, gestational hypertension, and proteinuria. Overexpression of the A isoform of the STOX1 transcription factor (STOX1A) recapitulates PE in mice, and STOX1A overexpressing trophoblasts recapitulate PE pa...

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Detalles Bibliográficos
Autores principales: Chatre, Laurent, Ducat, Aurélien, Spradley, Frank T., Palei, Ana C., Chéreau, Christiane, Couderc, Betty, Thomas, Kamryn C., Wilson, Anna R., Amaral, Lorena M., Gaillard, Irène, Méhats, Céline, Lagoutte, Isabelle, Jacques, Sébastien, Miralles, Francisco, Batteux, Frédéric, Granger, Joey P., Ricchetti, Miria, Vaiman, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389306/
https://www.ncbi.nlm.nih.gov/pubmed/35964341
http://dx.doi.org/10.1016/j.redox.2022.102406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389306/
https://www.ncbi.nlm.nih.gov/pubmed/35964341
http://dx.doi.org/10.1016/j.redox.2022.102406

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