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Stretch stress propels glutamine dependency and glycolysis in optic nerve head astrocytes

Glaucoma is an optic neuropathy that leads to irreversible blindness, the most common subtype of which is typified by a chronic increase in intraocular pressure that promotes a stretch injury to the optic nerve head. In rodents, the predominant glial cell in this region is the optic nerve head astro...

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Detalles Bibliográficos
Autores principales: Pappenhagen, Nathaniel, Yin, Eric, Morgan, Autumn B., Kiehlbauch, Charles C., Inman, Denise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389405/
https://www.ncbi.nlm.nih.gov/pubmed/35992925
http://dx.doi.org/10.3389/fnins.2022.957034