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Endophenotypic effects of the SORL1 variant rs2298813 on regional brain volume in patients with late-onset Alzheimer’s disease

Introduction: Two common variants of sortilin-related receptor 1 gene (SORL1), rs2298813 and rs1784933, have been associated with late-onset Alzheimer’s disease (AD) in the Han Chinese population in Taiwan. However, neuroimaging correlates of these two SORL1 variants remain unknown. We aimed to dete...

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Detalles Bibliográficos
Autores principales: Chen, Chun-Yu, Lin, Yung-Shuan, Lee, Wei-Ju, Liao, Yi-Chu, Kuo, Yu-Shan, Yang, Albert C., Fuh, Jong-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389408/
https://www.ncbi.nlm.nih.gov/pubmed/35992588
http://dx.doi.org/10.3389/fnagi.2022.885090