Superinduction of immunosuppressive glioblastoma extracellular vesicles by IFN-γ through PD-L1 and IDO1

BACKGROUND: Glioblastoma (GBM), the most common primary brain tumor, has a median survival of 15–16 months. Immunotherapy is promising but GBM-mediated immunosuppression remains a barrier. GBMs express the interferon-gamma (IFN-γ)-responsive immunosuppressive molecules programmed cell death ligand 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Mi-Yeon, Aibaidula, Abudumijiti, Brown, Desmond A, Himes, Benjamin T, Cumba Garcia, Luz M, Parney, Ian F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389426/
https://www.ncbi.nlm.nih.gov/pubmed/35990703
http://dx.doi.org/10.1093/noajnl/vdac017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389426/
https://www.ncbi.nlm.nih.gov/pubmed/35990703
http://dx.doi.org/10.1093/noajnl/vdac017

Ejemplares similares