FKBP4 regulates 5-fluorouracil sensitivity in colon cancer by controlling mitochondrial respiration

Mitochondrial respiration and metabolism play a key role in the pathogenesis and progression of colon adenocarcinoma (COAD). Here, we report a functional pool of FKBP4, a co-chaperone protein, in the mitochondrial intermembrane space (IMS) of colon cancer cells. We found that IMS-localized FKBP4 is...

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Detalles Bibliográficos
Autores principales: Zhu, Zhenyu, Hou, Qingsheng, Wang, Bishi, Li, Changhao, Liu, Luguang, Gong, Weipeng, Chai, Jie, Guo, Hongliang, Jia, Yanhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389594/
https://www.ncbi.nlm.nih.gov/pubmed/35981890
http://dx.doi.org/10.26508/lsa.202201413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389594/
https://www.ncbi.nlm.nih.gov/pubmed/35981890
http://dx.doi.org/10.26508/lsa.202201413

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