Cargando…
Chemical and Enzymatic Methods for Post-Translational Protein–Protein Conjugation
[Image: see text] Fusion proteins play an essential role in the biosciences but suffer from several key limitations, including the requirement for N-to-C terminal ligation, incompatibility of constituent domains, incorrect folding, and loss of biological activity. This perspective focuses on chemica...
Autores principales: | Taylor, Ross J., Geeson, Michael B., Journeaux, Toby, Bernardes, Gonçalo J. L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389620/ https://www.ncbi.nlm.nih.gov/pubmed/35912579 http://dx.doi.org/10.1021/jacs.2c00129 |
Ejemplares similares
-
Protein–Protein Conjugates: Tyrosine Delivers
por: Geeson, Michael B., et al.
Publicado: (2020) -
Platform
for Orthogonal N-Cysteine-Specific
Protein Modification Enabled by Cyclopropenone Reagents
por: Istrate, Alena, et al.
Publicado: (2022) -
π-Clamp-Mediated
Homo- and Heterodimerization
of Single-Domain Antibodies via Site-Specific Homobifunctional Conjugation
por: Taylor, Ross J., et al.
Publicado: (2022) -
Strategies for Conditional
Regulation of Proteins
por: Nadendla, Karthik, et al.
Publicado: (2023) -
Entirely enzymatic nanofabrication of DNA–protein conjugates
por: Bernardinelli, Giulio, et al.
Publicado: (2017)