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Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway

BACKGROUND: Pulmonary hypertension (PH) is a progressive and fatal cardiopulmonary disease characterized by pulmonary vascular remodeling and increased pulmonary vascular resistance and artery pressure. Vascular remodeling is associated with the excessive cell proliferation and migration of pulmonar...

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Detalles Bibliográficos
Autores principales: Liu, Haitao, Zhang, Sha, Liu, Yi, Ma, Jing, Chen, Wei, Yin, Tao, Li, Tongbin, Liang, Bin, Tao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389662/
https://www.ncbi.nlm.nih.gov/pubmed/35986277
http://dx.doi.org/10.1186/s12931-022-02124-4