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Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway
BACKGROUND: Pulmonary hypertension (PH) is a progressive and fatal cardiopulmonary disease characterized by pulmonary vascular remodeling and increased pulmonary vascular resistance and artery pressure. Vascular remodeling is associated with the excessive cell proliferation and migration of pulmonar...
Autores principales: | Liu, Haitao, Zhang, Sha, Liu, Yi, Ma, Jing, Chen, Wei, Yin, Tao, Li, Tongbin, Liang, Bin, Tao, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389662/ https://www.ncbi.nlm.nih.gov/pubmed/35986277 http://dx.doi.org/10.1186/s12931-022-02124-4 |
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