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Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency

BACKGROUND: The generation of over 69 spliced HIV-1 mRNAs from one primary transcript by alternative RNA splicing emphasizes the central role that RNA processing plays in HIV-1 replication. Control is mediated in part through the action of host SR proteins whose activity is regulated by multiple SR...

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Detalles Bibliográficos
Autores principales: Dahal, Subha, Clayton, Kiera, Been, Terek, Fernet-Brochu, Raphaële, Ocando, Alonso Villasmil, Balachandran, Ahalya, Poirier, Mikaël, Maldonado, Rebecca Kaddis, Shkreta, Lulzim, Boligan, Kayluz Frias, Guvenc, Furkan, Rahman, Fariha, Branch, Donald, Bell, Brendan, Chabot, Benoit, Gray-Owen, Scott D., Parent, Leslie J., Cochrane, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389714/
https://www.ncbi.nlm.nih.gov/pubmed/35986377
http://dx.doi.org/10.1186/s12977-022-00605-4