Cargando…
Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency
BACKGROUND: The generation of over 69 spliced HIV-1 mRNAs from one primary transcript by alternative RNA splicing emphasizes the central role that RNA processing plays in HIV-1 replication. Control is mediated in part through the action of host SR proteins whose activity is regulated by multiple SR...
Autores principales: | Dahal, Subha, Clayton, Kiera, Been, Terek, Fernet-Brochu, Raphaële, Ocando, Alonso Villasmil, Balachandran, Ahalya, Poirier, Mikaël, Maldonado, Rebecca Kaddis, Shkreta, Lulzim, Boligan, Kayluz Frias, Guvenc, Furkan, Rahman, Fariha, Branch, Donald, Bell, Brendan, Chabot, Benoit, Gray-Owen, Scott D., Parent, Leslie J., Cochrane, Alan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389714/ https://www.ncbi.nlm.nih.gov/pubmed/35986377 http://dx.doi.org/10.1186/s12977-022-00605-4 |
Ejemplares similares
-
On a path toward a broad-spectrum anti-viral: inhibition of HIV-1 and coronavirus replication by SR kinase inhibitor harmine
por: Dahal, Subha, et al.
Publicado: (2023) -
Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy
por: Wong, Raymond, et al.
Publicado: (2011) -
The RNA Splicing Response to DNA Damage
por: Shkreta, Lulzim, et al.
Publicado: (2015) -
Defective control of pre–messenger RNA splicing in human disease
por: Chabot, Benoit, et al.
Publicado: (2016) -
Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication
por: Shkreta, Lulzim, et al.
Publicado: (2017)