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BRCA1/2 variants and copy number alterations status in non familial triple negative breast cancer and high grade serous ovarian cancer
BACKGROUND: While the role of BRCA1/2 genes in familial breast and ovarian cancer is well established, their implication in the sporadic form of both cancers is still controversial. With the development of poly (ADP-ribose) polymerase (PARP) inhibitors, the exact relationship between BRCA1/2 genes a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389734/ https://www.ncbi.nlm.nih.gov/pubmed/35986351 http://dx.doi.org/10.1186/s13053-022-00236-y |