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BRCA1/2 variants and copy number alterations status in non familial triple negative breast cancer and high grade serous ovarian cancer

BACKGROUND: While the role of BRCA1/2 genes in familial breast and ovarian cancer is well established, their implication in the sporadic form of both cancers is still controversial. With the development of poly (ADP-ribose) polymerase (PARP) inhibitors, the exact relationship between BRCA1/2 genes a...

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Detalles Bibliográficos
Autores principales: El Ansari, Fatima Zahra, Jouali, Farah, Fekkak, Rim, Bakkach, Joaira, Ghailani Nourouti, Naima, Barakat, Amina, Bennani Mechita, Mohcine, Fekkak, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389734/
https://www.ncbi.nlm.nih.gov/pubmed/35986351
http://dx.doi.org/10.1186/s13053-022-00236-y