Super-enhancer hijacking LINC01977 promotes malignancy of early-stage lung adenocarcinoma addicted to the canonical TGF-β/SMAD3 pathway

BACKGROUND: Lung adenocarcinoma (LUAD) is the leading cause of death worldwide. However, the roles of long noncoding RNAs (lncRNAs) hijacked by super-enhancers (SEs), vital regulatory elements of the epigenome, remain elusive in the progression of LUAD metastasis. METHODS: SE-associated lncRNA micro...

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Detalles Bibliográficos
Autores principales: Zhang, Te, Xia, Wenjie, Song, Xuming, Mao, Qixing, Huang, Xing, Chen, Bing, Liang, Yingkuan, Wang, Hui, Chen, Yuzhong, Yu, Xinnian, Zhang, Zeyu, Yang, Wenmin, Xu, Lin, Dong, Gaochao, Jiang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389757/
https://www.ncbi.nlm.nih.gov/pubmed/35982471
http://dx.doi.org/10.1186/s13045-022-01331-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389757/
https://www.ncbi.nlm.nih.gov/pubmed/35982471
http://dx.doi.org/10.1186/s13045-022-01331-2

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