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Ku70 affects the frequency of chromosome translocation in human lymphocytes after radiation and T-cell acute lymphoblastic leukemia

BACKGROUND: As one of the most common chromosomal causes, chromosome translocation leads to T-cell acute lymphoblastic leukemia (T-ALL). Ku70 is one of the key factors of error-prone DNA repair and it may end in translocation. So far, the direct correlation between Ku70 and translocation has not bee...

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Detalles Bibliográficos
Autores principales: Cheng, Zhenbo, Wang, Yupeng, Guo, Lihuang, Li, Jiancheng, Zhang, Wei, Zhang, Conghui, Liu, Yangxu, Huang, Yue, Xu, Keqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389784/
https://www.ncbi.nlm.nih.gov/pubmed/35986335
http://dx.doi.org/10.1186/s13014-022-02113-3