Colistin-degrading proteases confer collective resistance to microbial communities during polymicrobial infections

BACKGROUND: The increasing prevalence of resistance against the last-resort antibiotic colistin is a significant threat to global public health. Here, we discovered a novel colistin resistance mechanism via enzymatic inactivation of the drug and proposed its clinical importance in microbial communit...

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Detalles Bibliográficos
Autores principales: Lee, Do-Hoon, Cha, Ju-Hee, Kim, Dae-Wi, Lee, Kihyun, Kim, Yong-Seok, Oh, Hyo-Young, Cho, You-Hee, Cha, Chang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389796/
https://www.ncbi.nlm.nih.gov/pubmed/35982474
http://dx.doi.org/10.1186/s40168-022-01315-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9389796/
https://www.ncbi.nlm.nih.gov/pubmed/35982474
http://dx.doi.org/10.1186/s40168-022-01315-x

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